Endocrine Abstracts

Introduction: The differential diagnosis between Graves’ disease (GD) and gestational transient thyrotoxicosis (GTT) is difficult in the absence of history and clinical features of GD. In this study, we aimed to determine the role of peak systolic (PSV) and end-diastolic velocities (EDV) of the right and left inferior thyroid arteries (ITA) as measured by color-flow Doppler ultrasonography (CFDUSG) for discriminating GTT from treatment naive GD.Meth...

Objective: Cardiovascular diseases (CVD) are the most important cause of mortality in acromegaly patients. Noninvasive assessment of aortic stiffness which can be used as an predictor of atherosclerosis, may be of benefit in acromegaly patients for early diagnosis of CVD. We evaluated the aortic elasticity parameters of acromegalic patients in remission and compared with healthy controls.Methods and results: Study subjects consisted of 20 patients with a...

Introduction: Werner syndrome (WS) is an autosomal recessive disease characterized by premature aging, skin changes, gray hair, alopecia, muscle atrophy, osteoporosis, and cataracts and has a high frequency of association with rare neoplasms. In addition, some endocrinological abnormalities were manifested in this rare disease, such as hypogonadism, diabetes mellitus, hyperlipidemia. Atrophic changes of organs and systems such as skin, brain and genital organs were reported. H...

Introduction: Hashimoto’s thyroiditis (HT) is common autoimmune thyroid disorder and is predominantly the clinical expression of cell-mediated immunity leading to destruction of thyroid cells. Vitamin D plays a role in the regulation of immunity and cell proliferation. So, do the serum levels of vitamin D reduced in HT?Methods: We examined the medical records of the ‘Thyroid policlinic’ patients with or without HT. Vitamin D, thyroid autoa...

Papillary thyroid carcinoma (PTC) is most frequent endocrine cancer on the other hand papillary microcarcinoma can be seen increasing frequency in recent years. In this study we compare clinical and histopathological characteristics of thyroid papillary microcarcinoma and papillary thyroid carcinoma retrospectively.Eighty one PTC and 38 PMC total 119 patients followed between 2005 and 2009 were enrolled study. Average follow-up time is 35 months in PTC a...

TSH supression therapy with thyroid hormone is a mainstay of thyroid cancer treatment. Effectiveness of thyroid hormone therapy may be disrupted by nonadherence of the patient, interfering drugs, foods and intestinal disorders. We here present a case of papillary thyroid cancer with unsuccessful supression therapy.Case: A 38 year old woman, underwent total thyroidectomy for euthyroid multinodular goitre, with a pathological diagnosis of papillary thyroid...

Introduction: Insulin resistance is the decrease sensitivity of tissues in the body to insulin effect. Obesity, advanced age, sedentary life and smoking are the factors leading to an increase in insulin resistance. In our study, we aimed to evaluate the relationship between the insulin resistance and smoking in individuals without advanced age, obesity, high blood glucose levels and hypertension.Materials and methods: We included in this study 100 patien...

Introduction: Hypoglycemia is the most common endocrinological problem in emergency departments.Objective: To explore the causes of hypoglycemia in patients who were admitted to the emergency department with symptoms resembling hypoglycemia.Design: In our study, 225 hypoglycemia cases were evaluated from January 2000 to May 2008.Results: Of 225 hypoglycemia cases, 158 (70.2%) receiving treatment for diabetes ...

Objective: To document clinical and laboratory presentations of FSH-staining pituitary adenomas, and to compare pure FSH-staining adenomas with mixed FSH and other anterior pituitary hormones staining ones.Methods: We analysed our inpatient records for patients who underwent pituitary surgery, and analysed histopathological reports for FSH-staining pituitary adenomas. Immunostaining positivity was defined as immunostaining of ≥5% of the adenoma cel...

‘Nondippers’ are individuals with absence of anticipated nocturnal decrease in blood pressure (BP) and increased incidence of target organ damage. The pathogenesis of nondipper hypertension is not clear at present. We aimed to investigate the effect of overt and subclinical hypothyroidism on the development of nondipper blood pressure pattern via 24-hour ambulatory blood pressure monitoring. One hundred and nine normotensive patients with overt and subclinical hypoth...